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在HyperArc计划中单个同心多重目标的旋转误差的剂量测量效应:一个幻影和回顾性成像分析研究研究
Samane Golmakani1, Andrew N McGrath1, Timothy J Williams1
1W.P. Holman Clinic, Royal Hobart Hospital, Hobart, Tasmania, Australia.
Journal of applied clinical medical physics
|December 16, 2023
概括
对于单个隔离中心多重目标 (SIMT) HyperArc 计划,建议设置 0.5 度的旋转错误. 这样可以确保在使用Encompass系统时,为临床目标体积 (CTV) 提供足够的计划目标体积 (PTV) 覆盖.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 放射治疗规划 放射治疗规划
背景情况:
- 单个隔离中心多重目标 (SIMT) 超弧技术可以实现精确的辐射传递.
- 轮换设置错误可以显著影响治疗准确性和剂量分配.
- 准确的患者静止对于最大限度地减少分数内运动和设置变化至关重要.
研究的目的:
- 为了研究SIMT HyperArc计划中旋转设置错误的剂量测量后果.
- 为了评估使用Encompass固定系统治疗的患者的分数内旋转设置错误.
- 为了确定适当的规划目标体积 (PTV) 边缘,用于旋转错误.
主要方法:
- 利用Varian HyperArc系统创建球形PTV (5-15毫米直径) 的计划,在不同的同心偏移处.
- 在旋转误差 (0.5°-2°) 下评估的剂量参数 (平均剂量,最大剂量,D99%,D95%).
- 分析了使用Encompass系统治疗的患者的形光束CT (CBCT) 数据,以量化分数内旋转误差.
主要成果:
- 旋转误差高达2°导致最大目标位移2.7毫米,导致显著的剂量减少 (例如,在5毫米PTV中D99%的~50%).
- 平均剂量减少因PTV大小而异 (例如,在2度旋转时为5毫米PTV的~25%).
- 平均分数内旋转误差 (pitch, roll, yaw) 在Encompass系统中分别为0.17°,0.11°和0.12°左右.
结论:
- 0.5°旋转设置误差是计算额外PTV利率的安全门.
- 对于距离异中点4.4厘米以外的目标,建议增加0.7毫米的PTV边缘.
- 建议在使用Encompass系统的SIMT计划中使用0.5°旋转误差作为PTV保证金计算的基础.
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