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腹腔镜袖子胃切除术:对甲状腺肥胖患者的体重指数和甲状腺激素的影响
Omer Faruk Buk1, Sönmez Ocak1, Mustafa Safa Uyanik1
1Department of General Surgery, Samsun Research and Training Hospital, Atakum, Turkey.
概括
腹腔镜袖胃切除术 (LSG) 可以显著降低体重指数 (BMI),并改善肥胖患者的甲状腺激素水平. 这种减肥手术增强了甲状腺功能,并提供了对高正常甲状腺刺激激素 (TSH) 水平的保护.
科学领域:
- 内分泌学 在内分泌学.
- 腹部外科 腹部外科
- 代谢健康 代谢健康
背景情况:
- 肥胖是一个日益严重的全球健康问题,与甲状腺功能障碍有关.
- 增加的甲状腺刺激激素 (TSH) 水平,即使在高正常范围内,也与增加的发病率和死亡率有关.
- 肥胖会对甲状腺功能产生负面影响,需要有效的干预措施.
研究的目的:
- 评估腹腔镜袖子胃切除术 (LSG) 对体质指数 (BMI) 和甲状腺激素水平在肥胖患者中的影响.
- 为了评估甲状腺刺激激素 (TSH),自由三甲状腺素 (FT3) 和自由四甲状腺素 (FT4) 在LSG后的变化.
- 为了确定LSG在管理与肥胖相关的甲状腺功能异常方面的有效性.
主要方法:
- 研究了一组300名甲状腺肥胖患者的队列,这些患者在2019年至2021年期间接受了LSG.
- 身体质量指数 (BMI),TSH,FT3和FT4水平在手术前和手术后6个月和12个月被测量.
- 进行了统计分析,以比较手术前和手术后的甲状腺激素和BMI值.
主要成果:
- 平均BMI在LSG后6个月和12个月显著下降 (P<0.001).
- 在LSG后,平均TSH和FT4水平显著改善 (P<0.001).
- 手术后一年,FT3平均水平没有显著变化 (P=0.005).
结论:
- LSG是一种有效的减肥手术,可在肥胖人群中显著减肥.
- 在肥胖患者中,LSG对甲状腺激素平衡有有益影响.
- 该程序可以提供与肥胖症中高正常TSH水平相关的不良影响的保护.
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