血细胞髓瘤与双M带在血清蛋白电泳:一个诊断难题?
Sunayana Misra1, Anu Singh, Vijay Kumar
1Department of Pathology, ABVIMS and Dr. RML Hospital, Delhi, India.
Journal of cancer research and therapeutics
|December 16, 2023
概括
本案例研究澄清了在血细胞骨髓瘤 (PCM) 中的血清蛋白电泳 (SPE) 上的两个M波段可能是单克隆性,不一定是双克隆性骨髓瘤 (BGM). 准确的诊断对于有效的PCM管理至关重要.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 临床病理学 临床病理学
背景情况:
- 血细胞髓瘤 (PCM) 是血细胞的恶性增殖,导致末端器官损伤.
- 单克隆性甘美病 (MGM) 具有异常的血细胞产生单个免疫球蛋白 (Ig) 类型的特征,在血清蛋白电泳 (SPE) 上被检测为M蛋白或M带.
- 双克隆性胃病变 (BGM) 涉及SPE上的两个不同的M波段,由Ig类切换或独立的血细胞克隆引起.
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