在COVID-19大流行之前和期间比较妊娠糖尿病查方法:系统性审查
Xingge Sun1, Clare McKeaveney1, Helen Noble1
1School of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.
Journal of diabetes investigation
|December 16, 2023
概括
在COVID-19期间,孕期糖尿病 (GDM) 查从口服葡萄糖耐受性测试 (OGTT) 转向HbA1c,RPG或FPG. 这些替代方案的准确性很差,并增加了不良妊娠结果的风险.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 口服葡萄糖耐受性测试 (OGTT) 是检测妊娠糖尿病 (GDM) 的标准.
- 由于长时间住院感染的风险,COVID-19大流行需要对GDM查进行重新评估.
- 建议使用其他查方法,如HbA1c,随机血葡萄糖 (RPG) 和禁食血葡萄糖 (FPG).
研究的目的:
- 检查COVID-19大流行之前和期间GDM查方法的差异.
- 评估替代GDM选方法的准确性和安全性.
主要方法:
- 在五个数据库 (2016-2023) 中进行系统的文献搜索.
- 使用CASP检查清单进行包含的队列研究的质量评估.
主要成果:
- 在大流行之前,OGTT是GDM查的国际标准.
- 在疫情期间,HbA1c,FPG或RPG被建议作为OGTT替代品.
- 替代方法显示灵敏度低,可能低估了GDM患病率,并导致了不良结果.
结论:
- 较新的GDM查方法 (HbA1c,RPG,FPG) 显示精度不高,并增加了妊娠和新生儿不良后果的风险.
- 针对性,基于风险的GDM查在紧急情况下更有效.
- 进一步的研究是必不可少的,以探索和验证用于GDM查的OGTT的替代方案.
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