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Updated: Jul 8, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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佩尼西米德A和B,两种新型的Diels-older [4 + 2]循环添加,来自Penicillium herquei的雌激素

Mengyi Deng1, Yan Xiao2, Shu Wang2

  • 1School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, Sichuan, PR China; Southwest Jiaotong University, Affiliated Hospital, The Third People's Hospital of Chengdu, Chengdu 610000, Sichuan, PR China.

Bioorganic chemistry
|December 16, 2023
PubMed
概括

从Penicillium herquei中分离出了两种新型的雌激素循环载体和氧化衍生物. 几种化合物,包括类固醇3,通过抑制氧化和促炎细胞因子,表现出显著的抗炎作用.

关键词:
它具有抗炎活性,具有抗炎活性.计算的 (13)C NMR-DP4+ 分析.迪尔斯阿尔德 [4 + 2] 循环添加 类固醇 类固醇这种植物是Penicillium herquei.量子化学 ECD 计算方法

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