暴露和反应预防与强迫症障碍的成人和青少年的压力管理培训:一项随机临床试验
Joseph A Himle1, Andrew Grogan-Kaylor2, Matthew A Hiller2
1School of Social Work, University of Michigan, 1080 South University Ave, Ann Arbor, MI, 48109, USA; Department of Psychiatry, Medical School, University of Michigan, 1500 East Medical Center Dr., Ann Arbor, MI, 48109, USA.
Behaviour research and therapy
|December 16, 2023
概括
暴露和反应预防 (ERP) 显著优于压力管理治疗 (SMT) 治疗强迫症 (OCD) 在青少年和成人. 强迫症专用治疗对于有效,终身管理这种残疾状况至关重要.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 神经科学是一个神经科学.
背景情况:
- 强迫症是一种虚弱的心理健康状况,需要有效的治疗.
- 暴露和响应预防 (ERP) 是跨年龄组的强迫症治疗的公认疗法.
- 之前的研究并没有直接将标准化ERP协议与青少年和成人群体的活性控制疗法进行比较.
研究的目的:
- 评估标准化暴露和反应预防 (ERP) 协议与强迫症青少年和成年人的压力管理治疗 (SMT) 相比的有效性.
- 确定ERP在减少强迫症症状严重程度方面是否优于SMT.
- 评估接受ERP的青少年和成年参与者之间治疗结果的差异.
主要方法:
- 一个随机的,评估者盲目的,并行组优越性试验与126名被诊断患有强迫症的青少年和成人参与者进行.
- 参与者被分配到每周接受12个ERP或SMT的会议.
- 使用耶鲁-布朗强迫症强迫症尺度 (Y-BOCS) 在基线,治疗期间和治疗后测量了强迫症症状的严重程度.
主要成果:
- 与SMT相比,ERP在Y-BOCS得分上表现出明显更大的改善 (影响大小 = -0.72,p <.001).
- 治疗响应者在ERP组 (86%) 显著高于SMT组 (32%) (p < .001).
- 缓解率在ERP (39%) 与SMT (7%) (p < .001) 中也显著高,青少年和成人ERP组之间没有显著的治疗后差异.
结论:
- 一个单一的ERP协议在治疗青少年和成人强迫症患者方面明显优于SMT.
- 强迫症特异性治疗,如ERP,对于在患有这种疾病的个体中获得最佳结果至关重要.
- 这些发现强调了利用基于证据的,强迫症特异性干预措施,而不是SMT等非特异性疗法的重要性.
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