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Updated: Jul 8, 2025

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RNA G四重复体抑制了 Mycobacterium tuberculosis 中的 PE/PPE 转录的翻译

Ashish Kumar1, Vinay Kamuju2, Perumal Vivekanandan1

  • 1Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, India.

The Journal of biological chemistry
|December 16, 2023
PubMed
概括

在Mycobacterium结核病转录中,特别是PE/PPE基因中,RNA G-四重复合体 (rG4s) 非常丰富. 稳定这些rG4s可抑制细菌生长和基因表达,这表明它们是潜在的药物标.

关键词:
在G-quadruplex中使用.结核菌菌菌 (Mtb) 的存在对于PE/PPE基因而言,这是一个很好的选择.RNA G-四重复合体 (rG4s) 是一种缓慢生长的真菌菌.翻译翻译翻译翻译翻译翻译

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