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一个用于皮下注射单克隆抗体的容器模型

Xiaoxu Zhong1, Yikai Liu1, Arezoo M Ardekani1

  • 1School of Mechanical Engineering, Purdue University, West Lafayette, IN 47906, United States.

International journal of pharmaceutics
|December 16, 2023
PubMed
概括

皮下单克隆抗体 (mAb) 药理动力学可以通过新的隔间模型更好地理解. 该模型强调了运输速率如何影响mAb半衰期和生物可用性,这对于SC药物开发至关重要.

关键词:
生物可用性 生物可用性分区模型是分区模型.在FcRn表达细胞中.单克隆抗体是一种单克隆抗体.

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