心血管疾病与严重登革热的关联:系统性审查和元分析
Bijaya Kumar Padhi1, Mahalaqua Nazli Khatib2, Shilpa Gaidhane3
1Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Current problems in cardiology
|December 16, 2023
概括
患有心血管疾病 (CVD) 的人患严重登革热的风险明显更高. 密切监测和有针对性的干预对这些患者在登革热诊断时至关重要,以防止严重的结果.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 心血管疾病 (CVD) 和登革热对全球健康构成重大负担.
- 以前存在的心血管疾病可能会增加严重登革热后果的风险,需要进一步调查.
研究的目的:
- 系统地审查和评估心血管疾病 (CVD) 和登革热严重程度之间的关系.
- 为了评估患有先前存在心血管疾病的患者严重登革热的风险.
主要方法:
- 在多个数据库中进行系统的文献搜索,截至2023年11月25日.
- 包括主要研究报告CVD在严重和非严重的登革热患者群体.
- 使用R软件进行的元分析计算了聚合相对风险 (RR),并通过纽卡斯尔-太华尺度进行质量评估.
主要成果:
- 对包括274,576名登革热患者在内的5项研究的元分析显示,心血管疾病和严重登革热之间存在显著的关联.
- 总的相对风险 (RR) 为2.71 (95% CI:1.03至7.10),表明风险增加.
- 在包括的研究中发现了大量的异质性 (I2 = 79%).
结论:
- 有证据表明,心血管疾病和严重登革热之间存在着显著的关联.
- 预先存在心血管疾病的个体在被诊断出登革热时需要谨慎监测和量身定制的干预措施.
- 积极的管理策略对于减轻心血管疾病患者严重登革热后果至关重要.
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