在社区居住的老年人中,功能和其他相关的萨尔科佩尼亚因素:SCOPE研究
Rafael Moreno-González1, Josep Maria Cruzado2, Andrea Corsonello3
1Geriatric Unit, Internal Medicine Department, Hospital Universitari de Bellvitge, Systemic Diseases and Ageing Group, Cardiovascular, Respiratory and Systemic Diseases and Cellular Aging Program, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona. L'Hospitalet de Llobregat, Barcelona, Spain.
European journal of internal medicine
|December 16, 2023
概括
高龄人群中 Sarcopenia 与严重的慢性病 (CKD),年龄较大和功能限制有关. 对这些因素的早期评估对于管理老年人群中沙症和严重的沙症至关重要.
科学领域:
- 老年学是一门学科.
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
背景情况:
- 萨科佩尼亚是老年人严重的健康问题,通常与各种并发症有关.
- 之前关于肉类的研究,特别是它与慢性病 (CKD) 的关系,已经产生了不一致的结果.
- 了解与肉类相关的临床和实验室因素对于老龄化人口的有效管理至关重要.
研究的目的:
- 调查与社区居住的老年人中与肉类和严重肉类相关的临床和实验室变量.
- 专门研究功能测量的作用,包括估计的膜过率 (eGFR),在sarcopenia的背景下.
- 确定早期发现和治疗老年人肉类症的关键因素.
主要方法:
- 从SCOPE多中心前性队列研究中对75岁以上的社区成年人进行横截面分析.
- 综合老年病学评估包括社会人口统计,生活方式,临床,人类学和实验室数据.
- 使用EWGSOP2修订的标准定义了肉症及其严重程度;使用基于肌素和非肌素的eGFR方程确定了CKD阶段.
主要成果:
- 在1420名参与者中,肉症的患病率为10.6%,其中6%患有严重的肉症.
- 软骨症的独立预测因素包括年龄较大,较低的体重指数 (BMI),日常生活工具活动 (IADL) 的残疾,微型精神状态检查 (MMSE) 得分较低和骨质疏松症.
- 第4阶段的CKD,定义为基于非肌素的eGFR方程 (CKD-EPIBTP-B2M),与肉症有显著的关联,严重肉症的关联更加明显.
结论:
- 麻症在社区居住的老年人中普遍存在,并与严重的CKD,晚年,功能障碍 (IADL),认知能力下降,骨质疏松症和低BMI有关.
- 这些已识别的因素对于对患有肉类的老年人进行全面评估和管理至关重要.
- 应特别注意患有严重的肉症和同时存在的CKD的患者,以便及时干预.
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