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Updated: Jul 8, 2025

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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蛋白质家族和超级家族中的局部能量丧保护

Maria I Freiberger1, Victoria Ruiz-Serra2, Camila Pontes2

  • 1Laboratorio de Fisiología de Proteínas, Departamento de Química Biológica - IQUIBICEN/CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, C1428EGA, Argentina.

Nature communications
|December 16, 2023
PubMed
概括

这项研究引入了一种分析蛋白家族局部丧的方法,揭示了序列变化如何影响蛋白质的稳定性和功能. 这种方法有助于理解蛋白质的多样性和表征新的蛋白质,包括新出现的病原体的蛋白质.

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