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Updated: Aug 11, 2026

A Guided Materials Screening Approach for Developing Quantitative Sol-gel Derived Protein Microarrays
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A Guided Materials Screening Approach for Developing Quantitative Sol-gel Derived Protein Microarrays

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对分子的选 - - 挑战和机遇

Geoffrey A Holdgate1, Catherine Bardelle2, Sophia K Berry2

  • 1Hit Discovery, Discovery Sciences, R&D, AstraZeneca, Alderley Park, UK.

SLAS discovery : advancing life sciences R & D
|December 17, 2023
PubMed
概括

分子是稳定蛋白相互作用的小分子,经常增强治疗效果的目标-E3酶结合. 本综述涵盖了诱导接近,识别方法和对分子的选方法.

关键词:
竞争 竞争 竞争 竞争降解降解是一种降解.分子粘合剂是一种分子粘合剂.蛋白质的接近性接近性稳定 稳定 稳定 稳定在Ubiquitination中使用.无法实现的目标是无法实现的目标.

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Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...