离子液体克服物理和生物障碍的潜力
Elfa Beaven1, Raj Kumar1, Jeong Man An2
1Department of Pharmaceutical Sciences, School of Pharmacy, University of Texas at El Paso, El Paso, TX 79902, United States; Biomedical Engineering Program, College of Engineering, University of Texas at El Paso, El Paso, TX 79968, United States.
Advanced drug delivery reviews
|December 17, 2023
概括
离子液体 (ILs) 显示出对非侵入性药物输送的承诺,通过克服生物障碍,增强通过皮肤和口服的途径. 这次审查强调了ILs.
科学领域:
- 材料科学 材料科学 材料科学
- 制药科学 制药科学
- 生物技术是生物技术.
背景情况:
- 离子液体 (ILs) 在药物输送系统中的潜力得到了认可.
- 它们独特的物理化学特性,易于修改和功能化是关键.
- 对于非侵入性药物输送应用而言,ILs提供了设计灵活性,这对于非侵入性药物输送应用至关重要.
研究的目的:
- 审查离子液 (IL) 在非侵入性药物输送中的应用.
- 评估基于IL的系统的进展,以缓解生物和物理障碍.
- 提供影响IL配方系统运输的因素的概述.
主要方法:
- 对离子液体在非侵入性药物输送中的综合文献综述.
- 分析最先进的发展和研究结果.
- 评估IL在克服通过皮肤和口服输送的生物和物理障碍方面的特性.
主要成果:
- 离子液体显示出大量的潜力,可以不侵入性地输送小型和大型分子.
- ILs有效地减轻生物和物理障碍,增强通过皮肤和口服药物输送.
- 已经确定了影响IL基配方系统运输的关键因素.
结论:
- 离子液体是用于先进的非侵入性药物输送系统的多功能材料.
- 通过克服生物障碍,ILs促进治疗分子的运输,提高药物的疗效.
- 对基于IL的配方的进一步研究有望改善通过皮肤和口服输送策略.
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