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Updated: Jul 8, 2025

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
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线粒体核糖体蛋白L12通过调节线粒体生物发生和代谢重编程来强化肝细胞癌

Xingzhao Ji1, Zhen Yang2, Chensheng Li3

  • 1Department of Pulmonary and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China; Shandong Key Laboratory of Infections Respiratory Disease, Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.

Metabolism: clinical and experimental
|December 17, 2023
PubMed
概括

线粒体核糖体蛋白L12 (MRPL12) 通过改变线粒体代谢,驱动肝细胞癌 (HCC) 的进展. 准MRPL12为HCC治疗提供了一个潜在的治疗策略.

关键词:
代谢重编程是一种代谢重编程.线粒体中的线粒体.线粒体核糖体蛋白 L12 线粒体核糖体蛋白氧化酸化是一种氧化酸化.通过PI3K-AKT- mTOR通路进行.阴阳 1 阴阳 1

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