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一种多方面的方法,用于识别,验证和免疫性自然处理和在预测高度保存的SARS-CoV-2的免疫性

Tamar Ratishvili1, Huy Quang Quach1, Iana H Haralambieva1

  • 1Mayo Clinic Vaccine Research Group, Department of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Vaccine
|December 17, 2023
PubMed
概括

确定了新的SARS-CoV-2 T细胞表位,以创建下一代类疫苗. 这些保存的表位提供了对变异的广泛保护,解决了抗体减弱和免疫逃逸的担忧.

关键词:
细胞免疫力 细胞免疫力皮层预测预测的预测HLA分子中的HLA分子.免疫类药物 免疫类药物质谱测量质量谱测量类疫苗 类疫苗这就是SARS-CoV-2病毒.在SARS-CoV-2疫苗中使用.

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Conjugated Proteins02:50

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Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
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