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Updated: Jul 8, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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帕金森病认知衰退的病理相关:从分子到神经网络

Nikolai I Novikov1, Elena S Brazhnik1, Valentina F Kitchigina2

  • 1Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.

Biochemistry. Biokhimiia
|December 17, 2023
PubMed
概括

帕金森病 (PD) 涉及由于神经退行和蛋白质聚合而导致的认知障碍 (CI). 了解这些病理机制是开发用于PD患者运动和认知衰退的新疗法的关键.

关键词:
帕金森病是帕金森氏症的一种疾病.动物模型动物模型生物标志物 生物标志物认知障碍 认知障碍是一种认知障碍.多巴胺是多巴胺的一种.葡萄糖的低代谢.线粒体功能障碍 线粒体功能障碍神经炎症是一种神经炎症.神经传递病理学 神经传递病理学定子发射和磁共振成像 (断层扫描) 技术结构变化 结构变化α-synuclein 是一种同核蛋白.

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