在抑郁症患者中评估动脉刚性的评估
Burcu Sırlıer Emir1, Sevler Yıldız2, Aslı Kazgan Kılıçaslan3
1Department of Psychiatry, Elazığ Fethi Sekin City Hospital, Elazığ, Turkey.
Alpha psychiatry
|December 18, 2023
概括
抑郁症患者表现出较高的缩血压和动脉弹性模量,表明动脉硬性增加. 这些发现表明,动脉硬度参数可能作为抑郁症中的心血管风险标志物.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 医疗成像医学成像
背景情况:
- 抑郁症和心血管疾病 (CVD) 之间存在着已知的相关性.
- 将抑郁症与心血管疾病发病率和死亡率的增加联系在一起的潜在机制仍然不完全理解.
- 动脉硬是导致心血管疾病风险的一个潜在因素.
研究的目的:
- 在被诊断患有抑郁症的患者中使用超声波检查动脉硬度.
- 为了比较抑郁症患者和健康对照者之间的动脉硬度参数.
- 为了确定抑郁症中潜在的心血管疾病风险标志物.
主要方法:
- 该研究包括35名患有抑郁症的患者和35名健康对照.
- 测量包括常规血液检测,人体测量和血压.
- 用多普勒超声波来评估动脉和大腿动脉内心介质厚度和其他动脉硬度参数.
主要成果:
- 在抑郁症组,缩血压显著高于抑郁症组 (P=.028).
- 冠状动脉弹性模块是动脉刚性的指标,在抑郁症患者中显著升高 (P=.048).
- 发现大腿部顺应和普罗马зин等效剂量之间存在显著的负相关性 (P=.021,r=-0.389).
结论:
- 抑郁症与动脉硬性增加有关,由较高的静脉血压和动脉弹性模量证明.
- 动脉硬度参数需要作为抑郁症患者潜在的心血管风险标志物进行调查.
- 对心理药物对动脉硬的影响进行进一步的研究对于管理这种人群中心血管疾病风险至关重要.
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