老年健康成年人心声腔大小和功能的规范值:动脉样硬化多民族研究
medRxiv : the preprint server for health sciences
|December 18, 2023
概括
正常的衰老会导致老年人心脏的显著差异. 由于缺乏特定年龄标准,目前的心声回声指南可能会误诊健康的老年心脏为患病.
科学领域:
- 心脏病学 心脏病学
- 老年学是一门学科.
- 医疗成像医学成像
背景情况:
- 老年人 (≥65岁) 患病的心声图 (2DE) 值还没有得到很好的定义.
- 这项研究旨在确定健康老年人心脏结构和功能的标准2DE值.
研究的目的:
- 在健康的老年人中确定心室大小和功能的标准2DE值.
- 定义基于性别和种族/种族的规范价值观.
- 将MESA切断值的功能状态和预后性能与既定准则进行比较.
主要方法:
- 对来自多民族动脉样硬化研究 (MESA) 队列的608名健康老年人的横截面研究.
- 分析了室内大小和功能的2DE参数.
- 功能状态通过NT-proBNP,6分钟步行距离 (6MWD) 和堪萨斯城心肌病问卷 (KCCQ) 进行评估.
主要成果:
- 健康的老年人表现出较低的NT-proBNP,更高的6MWD和更好的KCCQ分数.
- 在性别和种族/种族群体之间观察到心脏结构和功能的显著差异.
- 现有的指导方针错误地认为81.6%的健康老年人患有心脏异常.
结论:
- 健康老龄化涉及性别和种族/种族特定的心脏重塑.
- 目前的心声回声指南需要更新,以考虑与年龄有关的心脏变化.
- 现有的指导方针可能导致老年人过度诊断心脏异常.
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