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NS2B-D55E和NS2B-E65D的变异是负责在NS2B-NS3蛋白酶活动之间的差异日本脑炎病毒基因型I和III在化模型中的化模型

Abdul Wahaab1,2, Yan Zhang1, Jason L Rasgon2

  • 1Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.

bioRxiv : the preprint server for biology
|December 18, 2023
PubMed
概括

日本脑炎病毒 (JEV) NS2B-NS3蛋白酶活性在基因型I和III之间有所不同. 在NS2B辅因子中的特定变异,特别是在55和65的残留物中,显著影响蛋白酶功能和JEV复制.

关键词:
日本脑炎病毒病毒.在NS2B-NS3蛋白酶中.裂变部位的裂变位置原性类基质基质是原性类基质.基因型 基因型 基因型蛋白酶活动的蛋白酶活性.

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