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Updated: Jul 8, 2025

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突变驱动的胎儿回归在结直肠癌中促进了表型可塑性

Slim Mzoughi, Megan Schwarz, Xuedi Wang

    bioRxiv : the preprint server for biology
    |December 18, 2023
    PubMed
    概括

    结肠直肠癌 (CRC) 耐药性涉及一个与LGR5+干细胞 (SCs) 共同演变的胎细胞 (OnF) 细胞状态. 针对OnF和SC状态对于CRC中持续的瘤回归至关重要.

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