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基因组学揭示了几乎类动物 (Paenungulata) 中几乎完美的多体结构
Jacob Bowman1, David Enard2, Vincent J Lynch1
1Department of Biological Sciences, University at Buffalo, SUNY, 551 Cooke Hall, Buffalo, NY, USA.
bioRxiv : the preprint server for biology
|December 18, 2023
概括
大象,鹿和海牛 (Paenungulata) 之间的进化关系仍然不确定. 新的家族基因组数据表明,这些群体可能代表着一个无法解决的进化分裂,或多体化.
科学领域:
- * 进化生物学 进化生物学
- * 哺乳动物的遗传学
- * 基因组学 是一个学科.
背景情况:
- * 哺乳动物超级顺序Paenungulata中的进化关系,包括大象 (Proboscidea),海 (Hyracoidea) 和海牛 (Sirenia),历史上一直受到争论.
- * 关于这些群体的精确分支顺序,先前的形态学,分子学和家族学研究得出了相互矛盾的结论.
研究的目的:
- 使用大规模的族系学数据集,推断Paenungulata内部强大的族系学关系.
- 为了调查这个群体内冲突的基因信号的原因.
主要方法:
- 从13,388个蛋白质编码基因的对齐的家族基因分析.
- 检查了261种Eutherian哺乳动物物种.
- 应用多种凝聚 (MSC) 建模和基因树分析.
主要成果:
- 基因树为Paenungulata.com中的三个可能的分支顺序提供了几乎相同的支持.
- 虽然MSC树倾向于Proboscidea+Hyracoidea分裂,但对于基因树的不确定性,不完整的谱系排序和内向存在显著证据.
- 只有8-10%的基因表现出显著的遗传学信号来拒绝Paenungulate多元化 (一个未解决的分支点).
结论:
- *这项研究表明,对Proboscidea,Hyracoidea和Sirenia之间分支顺序的任何最终解决方案的支持有限.
- *这些发现表明,Paenungulata可能代表一种近乎多体化,这是一个很难或不可能用当前数据解决的进化场景.
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