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Updated: Jun 15, 2026

A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations
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A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations

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单细胞发育起源的剖析和B细胞急性淋巴细胞白血病的转录异质性

Ilaria Iacobucci, Andy G X Zeng, Qingsong Gao

    bioRxiv : the preprint server for biology
    |December 18, 2023
    PubMed
    概括

    对B级急性淋巴细胞白血病 (B-ALL) 的单细胞RNA测序揭示了内异质性,并确定了特定的白血病细胞起源. 这种方法提炼了分类,并改善了治疗结果的预测.

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    Differentiation of Common Myeloid Progenitor Cells01:15

    Differentiation of Common Myeloid Progenitor Cells

    Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...