在皮质星球细胞中局部神经递质的网络级编码
bioRxiv : the preprint server for biology
|December 18, 2023
概括
局部神经递质输入触发了天体细胞网络中广泛的,持久的反应. 这些反应区分神经递质,并影响未来的网络活动,突出缓慢的星细胞-神经元通信.
科学领域:
- 神经科学是一个神经科学.
- 细胞生物学 细胞生物学
- 神经生理学 神经生理学
背景情况:
- 星球细胞是大脑中最丰富的非神经元细胞,是通过 (Ca2+) 信号调节神经元活动的重要电路组件.
- 天体细胞Ca2+活动表现出复杂的时空动态,从快速的亚细胞事件到缓慢的,全网络同步的活动.
- 星细胞网络活动影响着许多大脑过程,但驱动这些动态的输入仍然在很大程度上是未知的.
结论:
- 局部,短暂的神经递质信号在几分钟内被广泛的皮质天体细胞网络编码.
- 这项研究支持越来越多的证据表明,显著的天体细胞-神经元通信发生在缓慢的,网络级的时空尺度上.
- 这些发现为未来的研究提供了基础,将特定的天体细胞Ca2+活动模式与不同的功能输出和神经元活动的天体细胞调节联系起来.
相关概念视频
Glial Cells
Overview
The Spinal Cord
The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
Spinal Cord: Information Processing
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Peripheral Nervous System: Ganglia and Nerves
The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
Neuronal Communication
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Spinal Cord
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.


