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Updated: Jul 8, 2025

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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Published on: September 1, 2015

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在多素-1中引起ADPKD的Missense变体破坏细胞表面定位或多素通道功能

Kotdaji Ha, Gabriel B Loeb, Meyeon Park

    bioRxiv : the preprint server for biology
    |December 18, 2023
    PubMed
    概括

    自体主导多囊性病 (ADPKD) 是导致衰竭的主要原因. 新的生物测试揭示了变异性破坏多素-1 (PC1) 局部化或离子通道功能,这表明ADPKD的小分子疗法.

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