患有与神经发育障碍 (ND-CNVs) 相关的副本数变异的年轻人易怒
Jessica H Hall1, Samuel J R A Chawner1,
1Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom.
medRxiv : the preprint server for health sciences
|December 18, 2023
概括
具有罕见副本数变异 (CNVs) 的年轻人经历了显著更高的易怒率. 这种与易怒的遗传联系独立于其他精神疾病或智商 (IQ).
科学领域:
- 遗传学 遗传学 是一个
- 神经发育 神经发育
- 精神病学是一个精神病学.
背景情况:
- 罕见副本数变异 (CNVs) 与神经发育和精神病风险有关.
- 在儿童神经发育状况中,易怒是常见的,但其遗传原因尚不清楚.
- 很少有研究探讨了年轻人遗传变异和易怒性之间的联系.
结论:
- 易怒是ND-CNVs的年轻人的关键临床特征.
- 遗传变异,特别是ND-CNVs,与年轻人的易怒直接相关.
- 临床医生应该考虑这种增加的风险,以进行知情的管理和干预.
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