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在B细胞中对伊诺图祖马布臭胺素的反应和耐药性的基因组决定因素ALL

Yaqi Zhao, Nicholas J Short, Hagop M Kantarjian

    medRxiv : the preprint server for health sciences
    |December 18, 2023
    PubMed
    概括

    在CD22的遗传突变驱动B细胞急性淋巴细胞白血病中对伊诺图祖马布臭加米辛 (InO) 治疗的耐药性. 了解这些CD22逃生机制,包括高突变和DNA损伤反应改变,可以改善未来的治疗方法.

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