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肺部外结节自然杀手/T细胞淋巴瘤:临床表现,CT特征和患者结局

Shuang Li¹, Xin Fang¹, Ying Liu¹

¹Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.

Quantitative imaging in medicine and surgery

|December 18, 2023

概括

肺部外结节自然杀手/T细胞淋巴瘤 (ENKTCL) 是一种罕见且具有攻击性的淋巴瘤. 早期检测使用CT标志,如"漂浮船"和及时的化疗对于改善在这个具有挑战性的诊断生存至关重要.

科学领域:

在瘤学瘤学.
血液学血液学血液学
放射学放射学是一门学科.

背景情况:

肺部外节自然杀手/T细胞淋巴瘤 (ENKTCL) 异常罕见,限制了研究.
了解其临床和成像特征对于诊断和管理至关重要.

研究的目的:

调查临床表现,计算机断层扫描 (CT) 发现和肺ENKTCL的结果.
确定影响这种罕见淋巴瘤患者预后和生存的因素.

主要方法:

对23名肺ENKTCL患者的回顾性队列研究 (2010年1月至2023年1月).
分析临床特征,实验室发现,CT扫描和治疗策略.
使用Kaplan-Meier方法和日志等级测试进行生存分析.

主要成果:

单独或多个结节是最常见的CT发现 (30.4%).
人们经常观察到光环标志 (78.3%) 和漂浮船标志 (83.3%).
乳酸脱酶 (LDH) 的升高是常见的 (86.9%);中位数的整体存活期为1个月,随着化疗改善到5个月.

结论:

肺性ENKTCL是侵略性的,由于非特异性特征,经常被误诊.
在CT,实验室测试和失败的抗生素治疗中出现的"漂浮船标志"可能有助于诊断.
及时的化疗与改善的生存率有关,强调了早期检测的必要性.

关键词:

肺淋巴瘤是肺的淋巴瘤.计算机断层扫描 (CT) 是一种计算机断层扫描.自然杀手/T细胞淋巴瘤生存结果的结果.

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