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Updated: Jul 8, 2025

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一个允许的胺基N-甲基转移酶用于Dithiolopyrrolones

Xiaoyan Chen1, Rachel M Johnson1, Bo Li2

  • 1Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

ACS catalysis
|December 18, 2023
PubMed
概括

研究人员通过添加N-甲基组来鉴定了DtpM,这是合成抗真菌化合物硫素至关重要的酶. 这一发现有助于理解天然产品的生物合成,并开发新的治疗方法.

关键词:
这是一种N-甲基化.生物催化剂的生物催化剂这是一种全息素 (holomycin).基质的杂乱性 基质的杂乱性这种类型的类型是 thiolutin, thiolutin.

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