尿液测量棒用于查低资源环境中的血葡萄糖和胆红素:一项概念验证研究
Laura Pighi1, Davide Negrini1, Brandon M Henry2
1Section of Clinical Biochemistry and School of Medicine, University of Verona, Verona, Italy.
Advances in laboratory medicine
|December 18, 2023
概括
一个商业的尿液测量棒可以有效地选血葡萄糖和胆红素水平. 这项研究发现,测量棒结果与实验室测试结果之间存在很高的一致性,这表明其在临床环境中的有用性.
科学领域:
- 临床化学 临床化学
- 诊断测试 诊断测试 诊断测试
- 生物标记分析 生物标记分析
背景情况:
- 尿液测量棒广泛用于尿液分析.
- 探索用于血生物标志物查的替代性,具有成本效益的方法是有价值的.
- 临床检测可以提高诊断的可访问性.
研究的目的:
- 评估一个商业尿液测量棒,用于查血葡萄糖和胆红素.
- 为了比较测量棒的性能与已建立的实验室方法.
- 评估尿液测量棒用于血分析物检测的诊断潜力.
主要方法:
- 使用罗氏COBAS 8000分析了60个人体血样本.
- 将10μL的血应用于商业尿液测量棒.
- 将半定量测量棒结果与定量实验室检测结果进行比较.
主要成果:
- 对血葡萄糖 (斯皮尔曼的r=0.83) 和胆红素 (斯皮尔曼的r=0.78) 观察到高相关性.
- 对于葡萄糖和胆红素,累计协议为88%.
- 卡帕的统计数据显示了实质性的协议 (葡萄糖为0.75,胆红素为0.76).
结论:
- 商用尿液测量棒在查血葡萄糖和胆红素方面表现出可接受的性能.
- 滴针查显示与参考实验室检测有很高的一致性.
- 这种方法提供了一个潜在的有用,可访问的工具,用于对血分析物的初步评估.
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