怀孕早期血清费里水平与中国人口甲状腺功能和怀孕结果之间的关联

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Xing Li¹, Zhuyuan Zhang¹, Wen Cai¹

¹Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, People's Republic of China.

International journal of women's health

|December 18, 2023

概括

看不见的铁缺乏症,通过低血清费里丁 (sFer) 表示,影响中国妇女的甲状腺功能和怀孕结果. 早期解决低SFer对于母亲和胎儿的健康至关重要.

科学领域:

产科和妇科产科和妇科
内分泌学在内分泌学.
营养科学营养科学

背景情况:

隐形的铁缺乏症,定义为低血清铁素 (sFer),在中国孕妇中没有得到充分的研究.
目前关于缺铁和甲状腺激素的研究主要集中在非孕妇或健康人群中.

研究的目的:

研究血清费里 (sFer) 状态对甲状腺功能和怀孕结果的影响.
评估在中国孕妇中隐形缺铁的患病率和影响.

主要方法:

上海总医院对781名单身孕妇进行了回顾性队列研究.
参与者根据血清费里 (sFer) 四分位数被分为四组.
统计分析包括二进制物流回归,单向ANOVA和千平方测试.

主要成果:

增加sFer度与早产发病率的降低和流产的威胁相关.
较低的sFer水平与母亲年龄较大和妊娠早期血清三甲状腺素 (γT3) 和自由甲状腺素 (FT4) 的降低有关.

结论:

第一个三个月的血清费里丁 (sFer) 水平显著影响甲状腺功能.
纠正看不见的铁缺乏症和在怀孕前或早期保持足够的sFer状态对于最佳的甲状腺功能和胎儿发育至关重要.
临床医生应优先监测孕妇的sFer状态,而不仅仅是标准的铁水平评估.

关键词:

孕妇孕妇孕妇孕妇血清费里素的使用情况亚临床的甲状腺功能低下症甲状腺激素是甲状腺激素的一种.甲状腺刺激激素激素激发甲状腺刺激激素.

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