机械通风COVID-19重症监护病房患者肺胸部的决定因素,一个单一中心研究
Tsegaye Gebreyes Hundie1,2, Zewdie Aderaw Alemu3, Lidiya Zenebe Getachew4
1Department of Research and Training, Eka Kotebe General Hospital, Addis Ababa, Ethiopia.
Journal of multidisciplinary healthcare
|December 18, 2023
概括
肺胸炎是COVID-19患者患有急性呼吸困扰综合征 (ARDS) 的严重并发症,需要侵入性通风. 这项研究确定了ARDS和侵入性通风作为与埃塞俄比亚ICU患者肺胸部相关的重要因素.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 在全球范围内,COVID-19的流行病已经造成数百万人的死亡,严重的病例导致急性呼吸困扰综合征 (ARDS),多器官衰竭和死亡.
- 肺胸炎是COVID-19重症监护室 (ICU) 患者报告的一种并发症,特别是那些接受侵入性通风的人.
- 了解与肺胸部相关的因素对于改善COVID-19重症患者的治疗结果至关重要.
研究的目的:
- 评估埃塞俄比亚亚的斯亚贝巴机械通风的COVID-19重症监护室患者中与肺胸部相关的因素.
- 确定在这种脆弱患者群体中促进肺胸部发病的特定风险因素.
主要方法:
- 采用病例控制研究设计,从2022年8月1日至31日期间涉及281名患者 (94例病例,187例对照).
- 数据采集使用ODK上预先测试的结构化定量工具,并使用SPSS版本26进行分析.
- 使用二进制逻辑回归来分析变量关联,统计显著性设置为0.05.05的p值.
主要成果:
- 在对混因素进行调整后,多变量分析显示,急性呼吸困扰综合征 (ARDS) 和肺胸之间存在显著的关联 (调整的几率比率[AOR] = 0.214,95%信心区间[CI] (0.088,0.519),P=0.001).
- 侵入性通风也与肺胸发生显著相关 (AOR=0.311,95% CI (0.121,0.796),P=0.015).
结论:
- 肺胸仍然是ARDSCOVID-19患者的常见且可能致命的并发症,即使采取了预防措施.
- ARDS和侵入性机械通风被证实是肺胸部发展的重要危险因素.
- 建议加强ICU设备和人员培训,以减轻这种并发症.
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