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肺内并发性病变在区分非新生和新生地质玻璃结节中的潜在作用
Bin-Jie Fu1, Xiao-Chuan Zhang1,2, Fa-Jin Lv1
1Department of Radiology, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Journal of inflammation research
|December 18, 2023
概括
肺内病变有助于区分非新生体和新生体地玻璃结节 (GGNs). 同时出现的固体结节和纤维化/化是非新发性GGN的关键指标,提高了诊断的准确性.
科学领域:
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 地玻璃结节 (GGNs) 需要精确区分瘤和非瘤原因.
- 区分这些GGN类型对于适当的患者管理和治疗策略至关重要.
研究的目的:
- 评估肺内并发病变的诊断价值,以区分非新发性与新发性GGN.
- 评估这些同时发生的病变对提高GGN分类准确性的影响.
主要方法:
- 追溯分析了395名非瘤和583名瘤GGN患者的临床和胸部CT数据 (2014年1月 - 2022年3月).
- 两组之间的目标GGN和肺内并发病变的CT特征的比较.
- 后勤回归分析以确定非新形成性GGN的独立预测因子.
主要成果:
- 肺内病变在非新发性GGN (87.88%) 和新发性GGN (82.18%) 之间更频繁.
- 非新形成性GGN显示多重固体结节的发病率更高,碎玻璃不透明/巩固,纤维化/化.
- 结合并发病变的预测模型改善了诊断准确度 (AUC从0.894到0.926).
结论:
- 同时在同一个叶片中出现多个固体结节和纤维化/化是非新生性GGN的重要指标.
- 这些发现,以及临床和目标GGN特征,增强了GGN的差异化.
- 建议考虑肺内同时发生的病变,以改善GGN诊断.
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