客观睡眠和心脏代谢生物标记:来自矿山研究社区的结果
Steven Zamora1, Kelsie M Full2, Erica Ambeba3
1Department of Climate, Atmospheric Sciences, and Physical Oceanography, Scripps Institution of Oceanography, UCSD, La Jolla, CA, USA.
Sleep advances : a journal of the Sleep Research Society
|December 18, 2023
概括
睡眠健康维度显示,对心脏代谢疾病 (CMD) 风险有不同的影响. 这些关联在研究队列中没有因西班牙裔种族而异.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 心脏代谢性疾病 (CMD) 构成严重的健康风险,睡眠健康方面可能会影响其发展.
- 西班牙裔人对睡眠不足和CMD生物标志物都有更高的风险.
- 了解睡眠如何影响不同种族的CMD对于有针对性的健康干预至关重要.
研究的目的:
- 调查多个睡眠健康维度 (持续时间,效率,质量) 和心脏代谢疾病 (CMD) 生物标志物之间的关联.
- 确定西班牙裔种族是否会改变睡眠健康和CMD生物标志物之间的关系.
主要方法:
- 采用了来自矿山社区 (CoM) 研究的数据,其中包括602名种族多样化的参与者.
- 使用加速度计 (持续时间,效率) 和自我报告 (质量) 测量睡眠.
- 采用多变量和定量回归模型来评估睡眠-CMD生物标志物协会,控制共变量和测试种族差异.
主要成果:
- 睡眠时间的增加与较高的低密度脂蛋白胆固醇有关.
- 睡眠效率低下与90百分位的胰岛素抵抗性更大相关.
- 自我报告的睡眠质量与CMD结果没有关联;没有观察到西班牙裔种族对效果的修改.
结论:
- 睡眠健康维度与心脏代谢疾病生物标志物具有复杂且有时矛盾的关联.
- 观察到的睡眠-CMD关系在这个队列中的西班牙裔种族基础上没有显著差异.
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