在一项前性医院研究中,中风后发作,和死亡率
Sofia Freiman1,2, W Allen Hauser3, Flora Rider1
1Moscow Research and Clinical Center for Neuropsychiatry of the Healthcare Department of Moscow, Moscow, Russia.
Frontiers in neurology
|December 18, 2023
概括
脑卒中后 (PSE) 影响了6.6%的中风幸存者,随着流域心脏病发作和下降的功能状态排放增加风险. 在PSE患者中,早期发作和神经状况恶化是常见的.
科学领域:
- 神经学 神经学
- 发病学 (Epileptology) 是一个专业的学科.
- 脑卒中医学 脑卒中医学
背景情况:
- 脑卒中后 (PSE) 是一种严重的并发症,特别是在老年人中.
- 在这个人口群体中,中风是的主要原因.
- 风险因素包括皮质病变,中风严重程度,年轻年龄和早期发作.
研究的目的:
- 确定PSE的发生率.
- 在潜在的中风后队列中确定PSE的风险因素.
主要方法:
- 对急性缺血性和出血性中风患者的前性单一医院研究.
- 对发作和复发性中风进行了为期2年的随访.
- 发病率/死亡率的卡普兰-梅尔曲线;预测因素的多变量回归.
主要成果:
- 招募了424名患者;6.6%的人患上了PSE (28/424).
- 累计PSE风险:15.4% (出血性) 与8.7% (缺血性) 相比.
- 缺血性PSE预测因素:流域心脏病发作 (HR 6.01) 和低巴塞尔指数 (HR 0.98). PSE患者的神经状况更差,恢复速度更慢.
结论:
- 流域中风和低排放巴特尔指数是缺血性中风的独立PSE风险因素.
- 早期发作和出院时神经状况恶化与PSE有关.
- 研究结果阐明了在缺血性中风后易患PSE的机制.
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