高血粘度在急性缺血性中风中的高血粘度
Jihoon Kang1, Ju Seok Oh2, Beom Joon Kim1
1Department of Neurology, Cerebrovascular Center, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Frontiers in neurology
|December 18, 2023
概括
血粘度升高与缺血性中风有关. 在医院抵达时测量血液粘度可能有助于区分缺血性中风和中风模仿.
科学领域:
- 生物医学工程 生物医学工程
- 神经学 神经学
- 血液学 血液学 血液学
背景情况:
- 血液粘度会影响血管壁的剪切应力.
- 关于血液粘度对血栓形成和急性中风的影响的证据有限.
- 研究血液粘度在中风中的作用至关重要.
研究的目的:
- 为了研究血液粘度对中风的影响.
- 评估疑似中风患者立即血液粘度测量的临床效用.
主要方法:
- 在症状发作后24小时内注册了疑似中风的患者.
- 在注射液体之前使用临床测试进行血液粘度测量.
- 在缺血性中风,出血性中风和中风模仿组中比较血液粘度.
主要成果:
- 血粘度在缺血性中风患者 (24.2 cP) 中显著更高,相比于中风模仿者 (17.8 cP),在10 rad/sec (p < 0.001) 时.
- 这种差异在多个振荡频率中是一致的.
- 接收器操作曲线下的面积用于区分中风与模仿器的区别是0.79.
结论:
- 缺血性中风与全血粘度的增加有关.
- 血液粘度测量显示出在区分缺血性中风与其他疾病方面具有潜在的临床实用性.
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