饮食质量指数-国际分数与卵巢储备减少的风险之间的关联:一个病例对照研究
Rahele Ziaei1, Hatav Ghasemi-Tehrani2, Minoo Movahedi3
1Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Frontiers in nutrition
|December 18, 2023
概括
坚持国际饮食质量指数 (DQI-I) 可能会改善卵巢储备,并降低接受生育治疗的女性卵巢储备减少 (DOR) 的风险. 较高的DQI-I得分与增加的毛囊数 (AFC) 和较低的DOR几率有关.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 营养科学 营养科学
- 妇女健康 妇女健康
背景情况:
- 有限的证据将饮食质量指数与生殖健康结果联系起来.
- 卵巢储备标志物,如毛囊数 (AFC) 和抗穆勒激素 (AMH),对于生育能力评估至关重要.
- 卵巢储备减少 (DOR) 是寻求生育治疗的女性的一个重大问题.
研究的目的:
- 调查国际饮食质量指数 (DQI-I) 和卵巢储备标记 (AFC和AMH) 之间的关联.
- 评估与DQI-I遵守相关的卵巢储备减少 (DOR) 的风险.
- 评估饮食质量对接受生育治疗的妇女的影响.
主要方法:
- 一项涉及370名女性的病例控制研究 (120名DOR,250名对照) 根据年龄和BMI进行了匹配.
- 用经过验证的食物频率问卷 (FFQ) 评估的饮食摄入量.
- 使用DQI-I评估饮食质量,包括多样性,充足性,适度和整体平衡.
主要成果:
- 增加对DQI-I的坚持与患有DOR的女性中较高的AFC有关.
- 经过对混因子进行调整后,较高的DQI-I得分与DOR的几率下降相关 (OR:0.39;95%CI:0.18-0.86).
- 该研究发现,饮食质量和卵巢储备标记之间存在保护性关联.
结论:
- 更多地遵守DQI-I可能会降低DOR风险,并改善被诊断患有DOR的女性的卵巢储备.
- 通过DQI-I评估的饮食质量显示,它有可能成为生殖健康的可修改因素.
- 建议通过前性研究和临床试验进一步验证.
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