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细胞外基质脱离的癌细胞通过增加基因素脱甲基酶KDM6活性来抵抗氧化应激

Mohamed A Alfaleh1,2, Mohammed Razeeth Shait Mohammed3, Anwar M Hashem2,4

  • 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Saudi journal of biological sciences
|December 18, 2023
PubMed
概括

抗细胞死亡的一种形式anoikis的癌细胞依赖KDM6A/B来维持糖解和谷氨酸代谢. 抑制KDM6A/B会破坏这些通路,增加活性氧物种 (ROS),导致细胞死亡.

关键词:
阿诺基斯的耐药性很强.葡萄糖溶解是什么? 葡萄糖溶解在KDM6A/B中使用.氧化应激是一种氧化应激.这就是ROSOS ROS.

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