抑郁症和焦虑指数之间的关联以及慢性阻塞性肺病中急性恶化的频率
Yu Jin Hong1, Youlim Kim2, Ji-Yong Moon3
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Therapeutic advances in respiratory disease
|December 18, 2023
概括
抑郁和焦虑使COPD患者的呼吸道症状和恶化率恶化,影响生活质量,但不会影响肺功能下降. 这些心理健康状况需要在慢性阻塞性肺病管理中加以关注.
科学领域:
- 肺部医学 肺部医学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 伴随性疾病显著影响慢性阻塞性肺病 (COPD) 的临床过程和预后.
- 了解COPD患者患有抑郁症和焦虑症等精神健康状况的具体影响,对于全面的护理至关重要.
研究的目的:
- 为了比较COPD患者的临床特征和恶化率,抑郁或焦虑或没有抑郁或焦虑.
- 研究抑郁和焦虑对COPD肺功能轨迹的影响.
主要方法:
- 利用了来自韩国COPD小组研究 (KOCOSS) 队列 (2012-2019) 的数据.
- 使用贝克抑郁 inventory和贝克焦虑 inventory评估抑郁和焦虑.
- 分析了线性混合模型的负双项回归和肺功能变化的恶化频率和肺功能变化.
主要成果:
- 患有抑郁症或焦虑症的患者表现出较差的肺功能,增加的症状负担 (mMRC,SGRQ,CAT得分) 和较高的过去一年恶化率.
- 抑郁症与中度至重度恶化的发病率增加1.57倍有关.
- 焦虑与中度至重度恶化率增加1.52倍和重度恶化率增加2.13倍有关.
结论:
- 慢性肺炎患者的抑郁和焦虑与呼吸系统症状的增加,恶化频率的增加和生活质量的降低有关.
- 在有或没有这些精神健康并发症的患者之间,在三年内没有观察到肺功能下降率 (FEV1) 的显著差异.
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