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硬度依赖的MSC定位和分化为CAFs - 对乳腺癌入侵的影响

Neha Saxena1,2, Soura Chakraborty3, Sarbajeet Dutta2

  • 1Department of Chemical Engineering, IIT Bombay,Mumbai 400076, India.

Journal of cell science
|December 18, 2023
PubMed
概括

迁移到转移前乳腺瘤的介质干细胞 (MSC) 分化为与癌症相关的纤维细胞 (CAF). 这些CAF增强了三阴性乳腺癌 (TNBC) 的侵袭和转移,特别是在更硬的细胞外基质上.

关键词:
癌症的入侵 癌症的入侵与癌症相关的纤维细胞细胞.不同化的差异化在ECM的硬度.介质细胞干细胞 介质细胞干细胞剪切压力压力是什么在TGFβ中,TGFβ是TGFβ.我们的 scRNAseqq.

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