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Updated: Jul 8, 2025

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

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由超抗原剂量控制决定的刺激强度FOXP3异型体的亚细胞定位和CD4+CD25+FOXP3+T细胞的抑制功能

Juyeun Lee1, Nogi Park1, Michael Nicosia2

  • 1Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS.

Journal of immunology (Baltimore, Md. : 1950)
|December 18, 2023
PubMed
概括

葡萄球菌超抗原可以通过促进调节性T细胞 (Tregs) 来诱导免疫抑制. 这项研究表明,低剂量的葡萄球菌肠毒素C1 (SEC1) 产生强大的Treg类细胞,而高剂量则不会,突出显示了刺激强度.

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