欧盟安全部队/EPOS2020关于慢性鼻炎与鼻的临床考虑情况的声明
Peter W Hellings1,2,3, Isam Alobid4,5,6, Wilma T Anselmo-Lima7
1Department of Microbiology and Immunology, Allergy and Clinical Immunology Research unit, KU Leuven, Leuven, Belgium.
对于严重的带鼻息肉的慢性鼻炎 (CRSwNP),本EUFOREA专家小组概述了口服皮质类固醇,鼻手术,生物制剂和阿司匹林脱敏 (ATAD) 的关键考虑因素,以指导个性化患者护理.
科学领域:
- 过敏和免疫学的过敏和免疫学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 呼吸系统药物 呼吸系统药物
背景情况:
- 严重的慢性鼻炎与鼻息肉 (CRSwNP) 需要超越标准护理的先进治疗策略.
- 目前欧洲过敏和呼吸道疾病研究和教育论坛 (EUFOREA) 的指导方针建议对不受控制的CRSwNP进行多种治疗选择.
研究的目的:
- 为专家小组提供对主要CRSwNP治疗的预期结果,考虑因素以及说明/禁忌的概述.
- 帮助医生和患者选择最佳的,个性化的治疗,治疗严重的失控CRSwNP.
主要方法:
- 专家小组对严重不受控制的CRSwNP的治疗选择进行了审查和共识.
- 对每个治疗方式的指示,结果,实用性,风险和成本的分析.
主要成果:
- 口服皮质类固醇,鼻外科手术 (初级和修复),生物治疗和阿司匹林脱敏 (ATAD) 是五个主要的治疗臂.
- 每种治疗都有独特的优势,特定的适应症,以及患者,医生和社会的重要考虑因素.
结论:
- 需要在CRSwNP中明确定义CRSwNP中每个处理支柱的标准.
- 本EUFOREA声明强调了针对严重不受控制的CRSwNP进行个性化治疗选择的重要性.
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