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Updated: Aug 10, 2026

Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
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Published on: January 16, 2017

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hGRAD:一个通用的"适合所有"系统,可从凝结物中急性耗尽RNA结合蛋白

Benjamin Arnold1, Ricarda J Riegger1, Ellen Kazumi Okuda1,2

  • 1Institute of Molecular Biosciences, Goethe University Frankfurt , Frankfurt am Main, Germany.

The Journal of cell biology
|December 18, 2023
PubMed
概括

一个新的系统,hGRAD,使核RNA结合蛋白 (RBPs) 的快速降解成为可能. 该工具有助于研究RBP功能,并揭示了短暂的转录变化和补偿机制.

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相关概念视频

Homologous Recombination02:31

Homologous Recombination

The basic reaction of homologous recombination (HR) involves two chromatids that contain DNA sequences sharing a significant stretch of identity. One of these sequences uses a strand from another as a template to synthesize DNA in an enzyme-catalyzed reaction. The final product is a novel amalgamation of the two substrates. To ensure an accurate recombination of sequences, HR is restricted to the S and G2 phases of the cell cycle. At these stages, the DNA has been replicated already and the...