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阿尔戈纳特2的核定位受细胞密度的影响,并可能缓解微RNAs的抑制

Krystal C Johnson1, Audrius Kilikevicius1, Cristina Hofman1

  • 1UT Southwestern Medical Center, Departments of Pharmacology and Biochemistry, Dallas, TX 75235, USA.

Nucleic acids research
|December 18, 2023
PubMed
概括

在特定条件下,阿尔戈诺特蛋白2 (AGO2) 转移到细胞核,去抑制基因标并增加细胞迁移. 这种局部化受到微RNA (miRNA) 处理和辅因子的影响,影响基因调节.

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