肝硬化患者的生存率:一项前性研究
Elena Curakova Ristovska1, Magdalena Genadieva-Dimitrova1, Beti Todorovska1
11University Clinic for Gastroenterohepatology, Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Skopje, RN Macedonia.
概括
患有急性失补偿症 (AD) 的肝硬化患者的生存率明显较短. 来自食道静脉的出血是最常见的死亡原因,突出了影响肝病生存的关键因素.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 内部医学 内部医学
- 临床研究 临床研究
背景情况:
- 肝硬化患者的生存时间因多种因素而有所不同.
- 急性失补偿 (AD) 是一个影响患者预后的关键事件.
- 了解死亡原因对于改善患者的治疗结果至关重要.
研究的目的:
- 为了评估肝硬化患者的一年生存率.
- 为了记录急性失补偿 (AD) 的发生率.
- 为了确定这一群体中主要的死亡原因.
主要方法:
- 对63名肝硬化患者进行了未来一年的随访.
- 评估阿尔茨海默病的发生,死亡原因和3,6个月和12个月的生存率.
- 患有AD和没有AD的患者之间的生存率的比较.
主要成果:
- 整体一年死亡率为38.09%,平均生存时间为108天.
- 来自食道静脉的出血是导致死亡的主要原因 (20.83%).
- 与没有AD患者 (229天) 相比,患有AD的患者的生存时间显著缩短 (97天);78.57%的AD患者在随访期间死亡.
结论:
- 病因,肝病阶段和AD的存在显著影响了肝硬化患者的存活率.
- 急性失补偿是死亡率的主要预测因素.
- 针对诸如食道静脉出血等并发症的治疗对于改善生存至关重要.
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