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对大肠杆菌Hsp70,DnaK及其核酸交换因子GrpE之间的复合物的结构和功能的新见解

Maria-Agustina Rossi1, Alexandra K Pozhidaeva1, Eugenia M Clerico1

  • 1Department of Biochemistry & Molecular Biology, University of Massachusetts Amherst, Amherst, Massachusetts, USA.

The Journal of biological chemistry
|December 18, 2023
PubMed
概括

像GrpE这样的核酸交换因子 (NEF) 通过结合其核酸结合域来调节热冲击蛋白70 (Hsp70) 的功能. 这项研究揭示了DnaK NBD/GrpE复合物的新模型,表明GrpE触发了全信号.

关键词:
70kDa的热冲击蛋白质可以产生热冲击.这就是DnaK的意思.在这里,GRPE.这是NMR的NMR.陪伴者是一个陪伴者.核酸交换因子是核酸的交换因子.

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