相关实验视频

Updated: Jul 8, 2025

Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution
07:30

Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution

Published on: October 7, 2016

8.2K

在哺乳动物中,Dgcr8功能在二级心脏场中,用于输出通道和右心室发育

Silvia E Racedo1, Yang Liu2, Lijie Shi1

  • 1Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.

Developmental biology
|December 18, 2023
PubMed
概括

在小鼠中,DGCR8基因失活会导致严重的心脏缺陷,包括持续性动脉和右心室低成形. 这项研究揭示了22q11.2删除综合征模型中微RNA处理影响心脏发育的早期分子变化.

关键词:
22q11.2 删除综合征Dgcr8 的使用方法心脏发育的心脏发育鼠标模型 鼠标模型第二个心脏场.

更多相关视频

En Face Endocardial Cushion Preparation for Planar Morphogenesis Analysis in Mouse Embryos08:57

En Face Endocardial Cushion Preparation for Planar Morphogenesis Analysis in Mouse Embryos

Published on: July 27, 2022

1.7K
In Vitro Generation of Heart Field-specific Cardiac Progenitor Cells09:29

In Vitro Generation of Heart Field-specific Cardiac Progenitor Cells

Published on: July 3, 2019

6.4K

相关概念视频

Development of the Heart01:27

Development of the Heart

The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
960
Chambers of the Heart01:16

Chambers of the Heart

The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
4.8K
Conduction System of the Heart01:20

Conduction System of the Heart

The cardiac conduction system produces and transmits electrical impulses that prompt myocardial contraction, ensuring efficient heart function. This intricate system ensures that the heart beats in a coordinated and efficient manner, beginning with the atria and then the ventricles. The conduction system optimizes cardiac output by maintaining this precise sequence, which is crucial for adequate blood circulation.
This system relies on the unique properties of nodal and Purkinje cells:...
1.0K
Coronary Circulation01:21

Coronary Circulation

The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
2.8K
Development of Blood Vessels01:07

Development of Blood Vessels

The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
594