肝功能障碍和未接种疫苗的COVID-19患者的临床结果,有或没有慢性乙型肝炎
Hao-Che Chang1, Tung-Hung Su2, Yu-Tsung Huang3
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
概括
患有COVID-19的慢性乙型肝炎患者经历了较高的肝酶水平和长时间住院. 升高的阿斯巴酸氨基转移酶 (AST) 表示严重的COVID-19和重症监护室入院风险.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 肝功能障碍是COVID-19的常见并发症之一.
- 对慢性乙型肝炎 (CHB) 患者的具体影响尚不清楚.
研究的目的:
- 为了研究COVID-19患者的肝功能障碍.
- 评估COVID-19对患有和没有CHB的患者的临床影响.
主要方法:
- 对109名未接种疫苗的COVID-19患者进行了回顾性队列研究.
- 基于乙型肝炎表面抗原 (HBsAg) 血清状态的分层.
- 对人口统计,实验室数据,住院过程和临床结果的分析.
主要成果:
- 阳性HBsAg患者的ALT和血小板水平较高,住院时间较长.
- 在肝炎,氧气使用,通风,特定治疗,ICU入院或死亡率方面没有显著差异.
- 老年和更高的AST与补充氧气相关;更高的AST预测了ICU入院.
- 氧气使用和休克与肝脏功能障碍有关.
结论:
- 在COVID-19期间,CHB患者表现出高ALT和更长的住院时间.
- 较高的AST水平预示着严重的COVID-19和ICU入院.
相关概念视频
Diseases of the Liver and Gallbladder
559
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
559
Esophageal Varices-II: Clinical Features and Management
71
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
71
Chronic Bowel Disorders: Introduction
456
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
456


