八十多岁的结肠直肠癌手术:现实世界的长期结果
Paul Willemsen1, Stefanie Devriendt2, Stijn Heyman2
1Dept. of General and Abdominal Surgery, ZNA Middelheim, Lindendreef 1, B-2020, Antwerp, Belgium. paul.willemsen@zna.be.
Langenbeck's archives of surgery
|December 18, 2023
概括
接受结直肠癌手术的老年患者 (80岁以上) 的5年生存率为41.5%. 应考虑为这些老年人提供最佳的手术和辅助治疗.
科学领域:
- 在瘤学瘤学.
- 老年医学 老年医学
- 手术瘤学手术瘤学
背景情况:
- 大肠直肠癌是老年人中普遍存在的腹内恶性瘤.
- 老龄化使得癌症患者的临床决策更加复杂.
- 预期寿命的增加导致更多的八十岁以上的人需要为结肠直肠癌进行重大手术.
研究的目的:
- 评估80岁及以上患者结直肠癌切除的结果.
- 分析这一人口群体的生存率和影响预后的因素.
主要方法:
- 对352名80岁以上的患者进行了回顾性评估,这些患者在2000年至2020年期间接受了结直肠癌手术
- 在术后活着超过90天的患者进行的生存分析.
主要成果:
- 332名患者进行了结直肠癌切除;57人在90天内死亡.
- 275名活着超过90天的患者的整体5年生存率为41.5%.
- 80-84岁和85岁以上的患者生存率没有显著差异;第四阶段癌症的生存率明显恶化 (p < 0.001).
结论:
- 经过结直肠癌切除术的八分生殖器患者实现了41.5%的5年生存率 (不包括90天死亡率).
- 选择适当的治疗对于这个患者群体至关重要.
- 最佳的手术和辅助疗法不应被拒绝给老年患者.
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