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相关概念视频

Ovarian Cycle01:27

Ovarian Cycle

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The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
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In Vitro Fertilization01:24

In Vitro Fertilization

284
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
284
Proliferative Phase01:20

Proliferative Phase

482
The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
482
Secretory Phase01:19

Secretory Phase

750
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
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相关实验视频

Updated: Jul 8, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

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在辅助生殖技术中支持质阶段.

Akanksha Garg1,2, Agata P Zielinska1,2, Arthur C Yeung1,2

  • 1Section of Endocrinology and Investigative Medicine, Imperial College London, Hammersmith Hospital, London, UK.

Nature reviews. Endocrinology
|December 19, 2023
PubMed
概括

在体外受精 (IVF) 过程中,质阶段的支持至关重要,但人们对其了解甚少. 本综述澄清了孕激素的使用情况.

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Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
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Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

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Human Egg Maturity Assessment and Its Clinical Application
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Human Egg Maturity Assessment and Its Clinical Application

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相关实验视频

Last Updated: Jul 8, 2025

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Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

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Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
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Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

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Human Egg Maturity Assessment and Its Clinical Application
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科学领域:

  • 生殖内分泌学 生殖内分泌学
  • 在体外受精过程中受精.
  • 胚胎学 胚胎学

背景情况:

  • 不孕症影响6对夫妇中的1对,而试管婴儿是常见的治疗方法.
  • 试管婴儿 (IVF) 卵巢刺激会扰乱自然的体阶段,损害植入和怀孕.
  • 目前的黄质阶段支持协议缺乏明确的最佳参数.

研究的目的:

  • 审查现有的关于试管婴儿中质阶段支持的证据.
  • 确定不确定性和未来的研究方向,以优化孕激素补充剂.
  • 为基于证据的黄阶段支持方案提供信息.

主要方法:

  • 对生理质期和IVF诱导的改变的文献综述.
  • 对荷尔蒙触发因素对质期支持需求的影响的评估.
  • 对子宫内膜受体性标志物和孕激素药理动学的分析.

主要成果:

  • 在试管婴儿中,超生理性卵巢刺激会导致功能障碍的白期.
  • 卵细胞成熟的荷尔蒙触发因素会影响所需的质阶段支持.
  • 了解子宫内膜转变和孕激素的作用是优化支持的关键.

结论:

  • 在试管婴儿中,用孕激素支持乳腺期是必不可少的,但需要进一步优化.
  • 澄清孕激素的最佳时间,剂量,途径和持续时间至关重要.
  • 未来的研究应该专注于个性化质期支持策略.