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Updated: Jul 8, 2025

In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells
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在HSP40家族的陪伴者异形DNAJB6b阻止神经元细胞从tau聚合

Ya-Lan Chang1, Chan-Chih Yang1, Yun-Yu Huang1

  • 1Department of Microbiology, College of Medicine, National Taiwan University, No. 1, Section 1, Jen-Ai Road, Taipei, 10051, Taiwan.

BMC biology
|December 19, 2023
PubMed
概括

DNAJB6b蛋白通过与tau的相互作用来防止阿尔茨海默病 (AD) 中的tau聚合. 降低的DNAJB6b水平与增加的tau病理相关,这表明它对AD的治疗潜力.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.一个是Cochaperone.DNAJB6bb DNAJB6b DNAJB6b DNAJB6b DNAJB6b DNAJB6b DNAJB6b DNAJB6b DNAJB6b DNAJB6b在J-域蛋白中.塔乌·塔乌 (Tau Tau) 是一个

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